منابع مشابه
Trimethoprim-sulfonamide combination therapy in early pregnancy.
QUESTION One of my patients presented with bacteriuria early in her pregnancy. Urine culture was positive for Escherichia coli. I would like to prescribe a trimethoprim-sulfamethoxazole combination because it worked well for her in the past. What is known about the safety of this medication during early pregnancy? ANSWER Evidence-based studies report an association between trimethoprim-sulfon...
متن کاملA naturally occurring gene amplification leading to sulfonamide and trimethoprim resistance in Streptococcus agalactiae.
Gene amplifications have been detected as a transitory phenomenon in bacterial cultures. They are predicted to contribute to rapid adaptation by simultaneously increasing the expression of genes clustered on the chromosome. However, genome amplifications have rarely been described in natural isolates. Through DNA array analysis, we have identified two Streptococcus agalactiae strains carrying t...
متن کاملMolecular basis of sulfonamide and trimethoprim resistance in fish-pathogenic Aeromonas isolates.
Sulfonamide-trimethoprim-resistant Aeromonas salmonicida and motile Aeromonas spp. from diseased fish of the GERM-Vet study carried the sul1 gene together with mostly cassette-borne trimethoprim resistance genes, including the novel gene dfrA28. The seven dfrA and dfrB genes identified were located mostly in class 1 integrons which commonly harbored other gene cassettes.
متن کاملResistance to trimethoprim and sulfonamides.
Sulfonamides and trimethoprim have been used for many decades as efficient and inexpensive antibacterial agents for animals and man. Resistance to both has, however, spread extensively and rapidly. This is mainly due to the horizontal spread of resistance genes, expressing drug-insensitive variants of the target enzymes dihydropteroate synthase and dihydrofolate reductase, for sulfonamide and t...
متن کاملSulfonamide Resistance of Clostridium Sporogenes.
Bacteria which are sulfonamide-sensitive have been reported to be incapable of the rapid utilization of folic acid for inhibition reversal (Alimchandani and Sreenivasan, J. Bacteriol. 73:538, 1957; Krieg and Pelczar, J. Bacteriol. 80:242, 1960; Davis and Feingold, p. 343. In I. C. Gunsalus and R. Y. Stanier [ed.], The Bacteria, vol. 4, Academic Press, Inc., New York, 1962), presumably because o...
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ژورنال
عنوان ژورنال: Antimicrobial Agents and Chemotherapy
سال: 1995
ISSN: 0066-4804,1098-6596
DOI: 10.1128/aac.39.2.279